CAS number: 10592-13-9;100929-47-3
Molecular formula: C22H25ClN2O8
molecular weight: 480.8955
Chemical structure:
Certificate of Analysis
Product Name | Doxycycline Hcl | |
Shelf life | 2 years | |
Test | Specification | Result |
Appearance | Yellow crystalline powder | Corresponds |
Identification | A)tR of HPLC test | Corresponds |
B)Sulphuric acid yellow Color reaction | Corresponds | |
C)Chloride's reaction | Corresponds | |
pH | 2.0 to 3.0 | 2.5 |
Specific Absorbance | 300-335 at 349nm,calculated on the Anhydrous,ethanol-free substance | 321 |
Light-absorbing Impurities | Not more than 0.07 at 490nm,calculated on the Anhydrous,ethanol-free substance | 0.03 |
Related Substances(%) | ||
6-epidoxycycline | Not more than 2.0% | 1.75 |
Oxytetracycline | Not more than 0.5% | 0.04 |
4-epidoxycycline | Not more than 0.5% | 0.03 |
4,6-epidoxycycline | Not more than 0.5% | N.D. |
Impurity F | Not more than 0.5% | 0.34 |
Any other impurities | Not more than 0.5% | 0.01 |
Ethanol(%) | 4.3 to 6.0% | 4.7 |
Heavy Metals(ppm) | Less than 50 ppm | <50< span=""> |
Water(%) | 1.4% to 2.8% | 2.1 |
Sulphated Ash(%) | Not more than 0.4% | <0.1< span=""> |
Assay(%) | 95.0-102.0% of C22H25CLN2O8,calculated on the Anhydrous,ethanol-free substance | 98.2 |
Conclusion | The Above Product Conforms to BP2012 |