CAS number： 95-25-0
Molecular formula： C7H4ClNO2
molecular weight： 169.57
Chemical structure：
Chlorzoxazone is a centrally acting muscle relaxant used to treat muscle spasm and the resulting pain or discomfort. It acts on the spinal cord by depressing reflexes. include dizziness,light headedness, malaise, nausea, vomiting, and liver dysfunction. Used with acetaminophen it has added risk of hepatoxicity,which is why the combination is not recommended. It can also be administered for acute pain in general and for tension headache (muscle contraction headache).
Chlorzoxazone used for various acute or chronic soft tissue (muscle, ligament sprain, contusion and muscle soreness after exercise, the central nervous lesion caused by muscle spasm and chronic fasciitis.
| Item | Specifications | Results |
| Appearance | White or almost white crystalline powder | Conforms |
| HPLC | The retention time of main peak corresponds with standard reference | Conforms |
| UA | Meet the requirements | Conforms |
| IR | Corresponds with standard reference | Conforms |
| Chloride | Not more than 0.02% | Conforms |
| Related substance | 2-Amino-4-chloro phenol :NMT0.5% | Conforms |
| p-chlorophenol: NMT 0.25% | ||
| Other impurities:NMT1.0% | ||
| Loss on drying | Not more than 0.5% | 0.10% |
| Residue on Ignition | Not more than 0.1% | 0.03% |
| Heavy metals (Pb) | Not more than 2mg/kg | Conforms |
| Assay | 98.5%min (on drying ) |
