Lamivudine

CAS number: 134678-17-4

Molecular formula: C8H11N3O3S

molecular weight: 229.26

Chemical structure:

ItemRequirements
DescriptionWhite to off- white crystalline powder
Light AbsorptionNot more than 0.015(440nm,4cm cell, 50mg/ml)
Water≤0.20% 
Light absorption(50mg/ml,440nm,4cm)≤0.0015
Limit of Lamivudine enantiomer≤0.30% 
Salicylic  acid≤0.10% 
Total impurities≤0.60% 
Other individual impurity≤0.10% 
Relative retention time at about 0.4 impurity≤0.30% 
Relative retention time at about 0.90 impurity≤0.20% 
Total residual solvents≤0.3% 
Ethanol≤0.20% 
n-Hexane≤0.029% 
Methylene dichloride≤0.06% 
TEA≤0.10% 
DMF≤0.088% 
Ethyl acetate≤0.20% 
Toluene≤0.089% 
Assay(On the anhydrous and solvent-free basis)98.0%~102.0%