Domperidone

CAS number: 57808-66-9

Molecular formula: C22H24ClN5O2

molecular weight: 425.91

Chemical structure:

Sr No.TestSpecificationResult
1DescriptionWhite crystalline powderComplies
2SolubilitySoluble in DMF, slightly soluble in methanolComplies
3Identification(A) (C) (D)Complies
4Melting point2440 – 2480C2470C
5Loss on dryingNMT 0.5 %0.15 %
6AssayLimit 99% to 101 %99.30 %
7Sulphated ashNMT 0.1 %0.012 %
8Related substance by  HPLC

Single impurityAny individual impurity Not More Than 0.25%  w/w0.18 %

Total impurityNot more than 0.5 % w/w0.37 %