Desogestrel

Other name : 258-929-4

DESTODENE

Desogestrel

Desogestrel (50 mg)

17a-Ethynyl-18-methyl-11-methyl-ene-D4-estren-17b-ol

(17R)-13-Ethyl-11-methylene-18,19-dinorpregn-4-en-20-yn-17-ol

(17a)-13-Ethyl-11-methylene-18,19-dinorpregn-4-en-20-yn-17-ol

(17alpha)-13-Ethyl-11-methylene-18,19-dinorpregn-4-en-20-yn-17-ol

Desogestrel for system suitability, European Pharmacopoeia (EP) Reference Standard

13-ethyl-17-ethynyl-11-methylene-1,2,3,6,7,8,9,10,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-17-ol

(8S,9S,10R,13S,14S,17R)-13-ethyl-17-ethynyl-11-methylene-1,2,3,6,7,8,9,10,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-17-ol

(8S,9S,10R,13S,14S,17R)-13-Ethyl-17-ethynyl-11-methylidene-1,2,3,6,7,8,9,10,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-17-ol

(8S,9S,10R,13S,14S,17R)-17-Ethinyl-13-ethyl-11-methyliden-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-ol

(8S,9S,10R,13S,14S,17R)-13-ethyl-17-ethynyl-11-methylidene-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-ol

(8S,9S,10R,13S,14S,17R)-13-éthyl-17-éthynyl-11-méthylidène-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tétradécahydro-1H-cyclopenta[a]phénanthrén-17-ol

(8S,9S,10R,13S,14S,17R)-13-Ethyl-17-ethynyl-11-methylene-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-ol (non-preferred name)

(8S,9S,10R,13S,14S,17R)-13-ethyl-17-ethynyl-11-methylidene-2,3,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-ol (non-preferred name)

CAS 54024-22-5

EINECS 258-929-4

Chemical formula C22H30O

Molecular weight 310.47

InChI InChI=1/C22H30O/c1-4-21-14-15(3)20-17-9-7-6-8-16(17)10-11-18(20)19(21)12-13-22(21,23)5-2/h2,8,17-20,23H,3-4,6-7,9-14H2,1H3/t17-,18-,19-,20+,21-,22-/m0/s1

Density 1.0169 (rough estimate)

Melting point 109-110 ° C

Boiling point 390.62 ° C (rough estimate)

Specific rotation D20+55 ° (chroroform)

Flash point 187.9 ° C

Steam pressure 3.92E-09mmHg at 25 ° C

Solubility Practically insoluble in water, very soluble in methanol, freely soluble in anhydrous ethanol and in methylene chloride

Refractive index 1.5100 (estimate)

Acidity coefficient 13.07 ± 0.40 (Predicted)

Storage conditions - 20 ° C Freezer

Appearance

Merck 14,2926

Crystallization with physical and chemical properties, melting point 109~110 ºC. [ α] D20+55 ° (chloroform).

The product is used as a powerful ovulation inhibitor, which can also change the consistency of cervical mucus and inhibit the development of endometrium