CAS number： 10592-13-9;100929-47-3
Molecular formula： C22H25ClN2O8
molecular weight： 480.8955
Chemical structure：
Certificate of Analysis
| Product Name | Doxycycline Hcl | |
| Shelf life | 2 years | |
| Test | Specification | Result |
| Appearance | Yellow crystalline powder | Corresponds |
| Identification | A)tR of HPLC test | Corresponds |
| B)Sulphuric acid yellow Color reaction | Corresponds | |
| C)Chloride's reaction | Corresponds | |
| pH | 2.0 to 3.0 | 2.5 |
| Specific Absorbance | 300-335 at 349nm,calculated on the Anhydrous,ethanol-free substance | 321 |
| Light-absorbing Impurities | Not more than 0.07 at 490nm,calculated on the Anhydrous,ethanol-free substance | 0.03 |
| Related Substances(%) | ||
| 6-epidoxycycline | Not more than 2.0% | 1.75 |
| Oxytetracycline | Not more than 0.5% | 0.04 |
| 4-epidoxycycline | Not more than 0.5% | 0.03 |
| 4,6-epidoxycycline | Not more than 0.5% | N.D. |
| Impurity F | Not more than 0.5% | 0.34 |
| Any other impurities | Not more than 0.5% | 0.01 |
| Ethanol(%) | 4.3 to 6.0% | 4.7 |
| Heavy Metals(ppm) | Less than 50 ppm | <50< span=""> |
| Water(%) | 1.4% to 2.8% | 2.1 |
| Sulphated Ash(%) | Not more than 0.4% | <0.1< span=""> |
| Assay(%) | 95.0-102.0% of C22H25CLN2O8,calculated on the Anhydrous,ethanol-free substance | 98.2 |
| Conclusion | The Above Product Conforms to BP2012 | |
