Cephradine

CAS number: 38821-53-3

Molecular formula: C16H19N3O4S

molecular weight: 349.4048

Chemical structure:

Product Name
Cefradine
Shelf Life
2 years
Tests
 BP2012 SpecificationsResults
Appearance
White or slightly yellow powder,hygroscopic powder.

White powder,

hygroscopic powder.
SolubilitySlightly soluble in water,practically insoluble in ethanol 96 percent and in hexane.Conform
IdentificationIR spectrum should match with that of standardConform
Clarity of solutionSolution S is not more opalescent than reference suspension II
Conform
Absorbance at 450nmNot more than 0.60.3
pH
Between 3.0 and 6.04.7
Specific optical rotation Between +80.0°and +90.0°(anhydrous substance)+85°
Related substances

Impurity BMaximum0.25%0.25%
Impurities A, C, D, E, F, GMaximum0.25%0.25%
Any other impurityMaximum0.5%0.5%
Total impurityMaximum2.0%2.0%
N,N-Dimethylaniline
Maximum 20 ppmNot used in process
Water
Maximum 6.0%determined on 0.300 g.4.3%
Sulphated ashMaximum 0.2%0.1%
Assay

cefradineMinimum 90.0%96.8%
cefalexinMaximum 5.0%1.5%
4′,5′-dihydrocefradineMaximum 2.0 %1.0%
Sum of cefradine, cefalexin and 4′,5′-dihydrocefradineMinimum 96.0%.and maximum 102.0%(anhydrous substance)99.3%